Multivariate vestibular testing: thresholds for bilateral Ménière's disease and aminoglycoside ototoxicity.
Identifieur interne : 001288 ( Main/Exploration ); précédent : 001287; suivant : 001289Multivariate vestibular testing: thresholds for bilateral Ménière's disease and aminoglycoside ototoxicity.
Auteurs : P S Dimitri [États-Unis] ; C. Wall ; S D RauchSource :
- Journal of vestibular research : equilibrium & orientation [ 0957-4271 ]
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Maladie de Ménière, Maladies des oreilles.
- induit chimiquement : Maladies des oreilles.
- intoxication : Aminosides.
- Diagnostic différentiel, Humains, Électronystagmographie, Épreuves vestibulaires, Études rétrospectives.
English descriptors
- KwdEn :
- MESH :
- chemical , poisoning : Aminoglycosides.
- chemically induced : Ear Diseases.
- diagnosis : Ear Diseases, Meniere Disease.
- Diagnosis, Differential, Electronystagmography, Humans, Retrospective Studies, Vestibular Function Tests.
Abstract
Although patient symptoms and an audiogram can typically identify the affected ear or ears in Ménière's disease, there are some cases where this differentiation is problematic. This paper concentrates on the sole use of vestibular test data to discriminate between unilateral and bilateral Ménière's disease. Patients that were known to have peripheral unilateral vestibular hypofunction (n = 104) were used as learning groups to define a region in multidimensional measurement space consisting of four vestibular test scores which summarized data from electronystagmography, sinusoidal harmonic acceleration, and computerized dynamic posturography tests. A multivariate boundary was created from the unilateral learning group that determined thresholds for identifying bilateral vestibular hypofunction. Patients with bilateral Ménière's disease (n = 23) and with bilateral ototoxicity (n = 19) were then used as test subjects to determine the sensitivity of the multivariate boundary. Results showed up to a increase in estimated test sensitivity (specificity = 95%) from 67%(current method)to 82%(new method)in identifying bilateral vestibular hypofunction.
PubMed: 12446964
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Wall</name></author><author><name sortKey="Rauch, S D" sort="Rauch, S D" uniqKey="Rauch S" first="S D" last="Rauch">S D Rauch</name></author></analytic><series><title level="j">Journal of vestibular research : equilibrium & orientation</title><idno type="ISSN">0957-4271</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aminoglycosides (poisoning)</term><term>Diagnosis, Differential (MeSH)</term><term>Ear Diseases (chemically induced)</term><term>Ear Diseases (diagnosis)</term><term>Electronystagmography (MeSH)</term><term>Humans (MeSH)</term><term>Meniere Disease (diagnosis)</term><term>Retrospective Studies (MeSH)</term><term>Vestibular Function Tests (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aminosides (intoxication)</term><term>Diagnostic différentiel (MeSH)</term><term>Humains (MeSH)</term><term>Maladie de Ménière (diagnostic)</term><term>Maladies des oreilles (diagnostic)</term><term>Maladies des oreilles (induit chimiquement)</term><term>Électronystagmographie (MeSH)</term><term>Épreuves vestibulaires (MeSH)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="poisoning" xml:lang="en"><term>Aminoglycosides</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Ear Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Ear Diseases</term><term>Meniere Disease</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladie de Ménière</term><term>Maladies des oreilles</term></keywords><keywords scheme="MESH" qualifier="induit chimiquement" xml:lang="fr"><term>Maladies des oreilles</term></keywords><keywords scheme="MESH" qualifier="intoxication" xml:lang="fr"><term>Aminosides</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Diagnosis, Differential</term><term>Electronystagmography</term><term>Humans</term><term>Retrospective Studies</term><term>Vestibular Function Tests</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Diagnostic différentiel</term><term>Humains</term><term>Électronystagmographie</term><term>Épreuves vestibulaires</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Although patient symptoms and an audiogram can typically identify the affected ear or ears in Ménière's disease, there are some cases where this differentiation is problematic. This paper concentrates on the sole use of vestibular test data to discriminate between unilateral and bilateral Ménière's disease. Patients that were known to have peripheral unilateral vestibular hypofunction (n = 104) were used as learning groups to define a region in multidimensional measurement space consisting of four vestibular test scores which summarized data from electronystagmography, sinusoidal harmonic acceleration, and computerized dynamic posturography tests. A multivariate boundary was created from the unilateral learning group that determined thresholds for identifying bilateral vestibular hypofunction. Patients with bilateral Ménière's disease (n = 23) and with bilateral ototoxicity (n = 19) were then used as test subjects to determine the sensitivity of the multivariate boundary. Results showed up to a increase in estimated test sensitivity (specificity = 95%) from 67%(current method)to 82%(new method)in identifying bilateral vestibular hypofunction.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12446964</PMID><DateCompleted><Year>2003</Year><Month>06</Month><Day>13</Day></DateCompleted><DateRevised><Year>2007</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0957-4271</ISSN><JournalIssue CitedMedium="Print"><Volume>11</Volume><Issue>6</Issue><PubDate><MedlineDate>2001-2002</MedlineDate></PubDate></JournalIssue><Title>Journal of vestibular research : equilibrium & orientation</Title><ISOAbbreviation>J Vestib Res</ISOAbbreviation></Journal><ArticleTitle>Multivariate vestibular testing: thresholds for bilateral Ménière's disease and aminoglycoside ototoxicity.</ArticleTitle><Pagination><MedlinePgn>391-404</MedlinePgn></Pagination><Abstract><AbstractText>Although patient symptoms and an audiogram can typically identify the affected ear or ears in Ménière's disease, there are some cases where this differentiation is problematic. This paper concentrates on the sole use of vestibular test data to discriminate between unilateral and bilateral Ménière's disease. Patients that were known to have peripheral unilateral vestibular hypofunction (n = 104) were used as learning groups to define a region in multidimensional measurement space consisting of four vestibular test scores which summarized data from electronystagmography, sinusoidal harmonic acceleration, and computerized dynamic posturography tests. A multivariate boundary was created from the unilateral learning group that determined thresholds for identifying bilateral vestibular hypofunction. Patients with bilateral Ménière's disease (n = 23) and with bilateral ototoxicity (n = 19) were then used as test subjects to determine the sensitivity of the multivariate boundary. Results showed up to a increase in estimated test sensitivity (specificity = 95%) from 67%(current method)to 82%(new method)in identifying bilateral vestibular hypofunction.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dimitri</LastName><ForeName>P S</ForeName><Initials>PS</Initials><AffiliationInfo><Affiliation>Harvard University-Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wall</LastName><ForeName>C</ForeName><Initials>C</Initials><Suffix>3rd</Suffix></Author><Author ValidYN="Y"><LastName>Rauch</LastName><ForeName>S D</ForeName><Initials>SD</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>DC00290</GrantID><Acronym>DC</Acronym><Agency>NIDCD NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>DC03219</GrantID><Acronym>DC</Acronym><Agency>NIDCD NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Vestib Res</MedlineTA><NlmUniqueID>9104163</NlmUniqueID><ISSNLinking>0957-4271</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000617">Aminoglycosides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CitationSubset>S</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000617" MajorTopicYN="N">Aminoglycosides</DescriptorName><QualifierName UI="Q000506" MajorTopicYN="Y">poisoning</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004427" MajorTopicYN="N">Ear Diseases</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004584" MajorTopicYN="N">Electronystagmography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008575" MajorTopicYN="N">Meniere Disease</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014724" MajorTopicYN="Y">Vestibular Function Tests</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2002</Year><Month>11</Month><Day>26</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>6</Month><Day>14</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2002</Year><Month>11</Month><Day>26</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12446964</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><noCountry><name sortKey="Rauch, S D" sort="Rauch, S D" uniqKey="Rauch S" first="S D" last="Rauch">S D Rauch</name><name sortKey="Wall, C" sort="Wall, C" uniqKey="Wall C" first="C" last="Wall">C. Wall</name></noCountry><country name="États-Unis"><region name="Massachusetts"><name sortKey="Dimitri, P S" sort="Dimitri, P S" uniqKey="Dimitri P" first="P S" last="Dimitri">P S Dimitri</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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